Get ready to bridge the gap between the classroom and your career! This event series is your gateway to the future of engineering. Explore different majors, discover the in-demand skills companies are looking for, and connect directly with industry professionals. Don't just study engineering—build the career you want.

*This is a HMAW1905-recognized event in the “Personal Enrichment & Community Service”
category under the "Self-directed Experience" of HMAW1905: Behavioral Foundations of
University Education: Habits, Mindsets, and Wellness. To receive 1.5 hours, you must attend the
event in full and miss no more than 10 mins.

After the Super Typhoon Ragasa, massive amounts of debris and rubbish were washed onto the HKUST seafront. This popular spot—where students come to relax, unwind, and connect with the ocean—is now facing public health and environmental challenges. To prevent trash from flowing back into the sea and protect marine life, we invite you to join our beach cleanup. Help restore the shoreline and contribute to a cleaner, healthier campus environment.

超強颱風樺加沙帶來不少影響，但颱風過後，海浪將大量垃圾和碎片沖上香港科技大學的海濱。 這片學生常來放鬆、休憩、親近海洋的空間，現正面臨公共衛生與環境的挑戰。 為了減少垃圾回流海中、保護海洋生態，我們誠邀你參與海灘清潔活動，恢復海岸線的原貌，為校園環境出一分力。

Date: 2 Oct 2025 (Thu)
Time: 2:45 - 5:15pm
Gathering Time & Venue: 2:45pm @HKUST Campus

# You are required to attend the whole service program, including Briefing, Service & Debriefing.

Remark:

1. [HMAW1905] This is a recognized event in the "Self-directed Experience" component of HMAW1905: Behavioral Foundations of University Education: Habits, Mindsets, and Wellness. To receive 2.5 hours, you must attend the event in full and miss no more than 10 mins.

2. Successful applicants will receive a confirmation email from connect@ust.hk, and will be able to find their application status listed as "Confirmed" on the Social Career portal/app.

3. Upon completion of the service, the actual service hours will be subjected to the confirmation of the partner association.

4. Enquiry: saaudreyting@ust.hk

Sign up here by 30/09/2025 01:00PM

https://app.socialcareer.org/en/volunteers/3f8547d6-770a-4ade-b5ce-b952a4e95923

Sustainable Development Goal(s):SDG 14, SDG 15

Trees traditionally across cultures symbolize attributes like strength, resilience and the essence of nature. This 2-hour mixed media art making workshop offers you the opportunity to make personal connections with these metaphors through a guided step by step artmaking process. We will use paint, collage techniques and words to create a personalised "tree" representing the range of resources within. The visual image will help you recognise the strengths that are available to you and act as a reminder of your own capacities during times of challenge. No art experience is necessary.

This workshop is part of Project CREATE – an initiative designed to enhance students’ wellbeing and resilience through expressive arts.

Registration: Click HERE to register

Remarks: 

• Successful registrants will receive confirmation via email. 
• Students won't be allowed to join the workshop after it has started for 10 minutes.
• This is a HMAW1905-recognized workshop series in the “Personal Enrichment & Community Service” category under the "Self-directed Experience" of HMAW1905. You must attend the event in full and miss no more than 10 minutes to get 2 hours.
• The event is fully subsidized by the Dean of Students’ Office (DSTO). If you are unable to participate in the event as scheduled, you should send a written notification to ucreate@ust.hk as soon as possible but no later than 31 October 2025 (Fri). If you withdraw after the deadline or cannot fully attend the program with legitimate reasons supported by proof (illness or an exam conflict), DSTO reserves the right to charge you HK$380 program fee.

Enquiry: ucreate@ust.hk

How does a great day look to you? Join us for an engaging workshop where you can explore your Lumina Spark portrait and draw insights from it to set your day for success! In this interactive session, you will:

• Discover Your Strengths: Learn how to leverage your strengths as valuable resources in both your academic and personal life.
• Recognize Stress Signals: Identify key signs of stress through the Lumina Spark framework, helping you stay in tune with your well-being.
• Create Your Self-Care Routine: Get practical tips on developing a self-care routine that works for you.

RSVP: Click HERE to register by 24^th Oct 2025, noon.

Enquiry: ccp@ust.hk

Remarks: 

• This workshop is for students who have done Lumina Spark and attended the debriefing session ONLY.
• Successful registrants will receive a confirmation by email. 
• This is a HMAW1905-recognized event in the “Personal Enrichment & Community Service” category under the "Self-directed Experience" of HMAW1905: Behavioral Foundations of University Education: Habits, Mindsets, and Wellness. To receive 1.5 hours, you must attend the event in full and miss no more than 10 mins.

Abstract

Aβ was isolated and sequenced from the amyloid angiopathy of Alzheimer’s disease in 1984 and from plaque cores in 1985. By oligonucleotide hybridization the APP gene was cloned and localized to chromosome 21 in 1987. After a false start, APP mutations were identified in Dutch amyloid angiopathy in 1990 and in a minority of early onset Alzheimer families in 1990. In other families with early onset Alzheimer’s disease, mutations were described in the presenilin genes in 1995 and the effects of both APP and presenilin mutations on APP processing was described in 1996. Mice with APP and mice with APP and presenilin mutations which deposited plaques but not tangles were made in 1994-1998. MAPT mutations were found in tangle only dementias in 1998 and these mutations allowed mice with tangles to be produced in 2000. Crossing these tangle mice with the plaque mice potentiated tangle formation but did not alter plaque production showing tangles and cell loss were downstream or amyloid in the pathogenic cascade. This sequence of findings largely made from the analysis of early onset mendelian disease is what has underpinned the amyloid hypothesis. More recently, genetic analysis of the much more prevalent late onset disease has identified many loci, most of which are involved in microglial Aβ clearance.

This background justified the three major therapeutic approaches to Alzheimer’s disease based on either reducing Aβ production or facilitating Aβ clearance.

Aβ is produced by the sequential cleavage of APP by β-secretase at the N terminal of Aβ and γ-secretase at the C terminal of Aβ. With this background, there have been three major therapeutic targets: β-secretase inhibition, γ-secretase inhibition/modulation and amyloid removal by antibody. Both  β- and  γ-secretase inhibition failed in clinical trials possibly because both enzymes have many other substrates besides APP or because the build up of C-terminal stubs of APP was neurotoxic. Attempts at γ-secretase modulation (altering the cleavage site of the enzyme) continue. The major developments have come from the use of antibodies to either prevent amyloid build up or to facilitate amyloid removal.

The first hint that antibodies to Aβ might be a useful therapeutic strategy came from the experimental treatment of transgenic mice in 1999. However, while this first antibody and some of the other early antibodies prevented amyloid build up, they did not cause amyloid removal except where there was blood brain barrier damage. These antibodies failed in clinical trials. After these failures and the failures of β- and  γ-secretase inhibitors there was concern and disagreement in the research community about whether amyloid therapies were worth further pursuing. However, more recently, antibodies which caused amyloid removal, aducanemab (controversially), lecanemab and dononamab have all caused amyloid removal, and have led to modest clinical benefit and have therefore received some regulatory approval. All though, cause blood vessel inflammation (ARIA) as the antibodies hit the amyloid angiopathy.

In this lecture, the speaker will review these issues and discuss the genetic and pharmacologic attempts to both improve anti-amyloid therapies and to decrease their side effects. He will discuss how biomarker analyses, particularly plasma pTau, allow the detection and monitoring of amyloid pathology and will conclude by arguing that we should consider switching to biomarker driven clinical trials, analogous to monitoring high cholesterol as a surrogate for heart disease and stroke. In this example, statins were approved by FDA as medications 7 years before they were shown to have disease modifying effects on heart disease.


About the Speaker

Sir John Hardy  received his BS in Biochemistry from the University of Leeds in 1976 and his PhD in Neurochemistry from the Imperial College London in 1981. He spent his early career at the University of Newcastle upon Tyne, the University of Umea and St Mary's Hospital (which later merged with Imperial College London). He moved to the US to take up the position of Eric Pfeiffer Endowed Chair in Alzheimer's Research at the University of South Florida. He then joined the Mayo Clinic Jacksonville in 1996 as a Consultant and Professor of Pharmacology and chaired the Department of Neuroscience during 1999-2001. In 2001, he moved to the National Institute on Aging of the US National Institutes of Health as the Chief of Laboratory of Neurogenetics. He returned to the UK in 2007 as a Professor of Neuroscience at the University College London (UCL). He is currently the Chair of Molecular Biology of Neurological Disease at the UCL Institute of Neurology. Additionally, he has collaborated closely with faculty at HKUST and serves as one of the Team Leaders at the Hong Kong Center for Neurodegenerative Diseases (HKCeND).

Sir John’s research interests are in the genetic analysis of neurodegenerative disease. He contributed to a critical breakthrough in understanding what goes wrong in the brains of people suffering from Alzheimer’s disease, the most common form of dementia. He has since led a broader effort to understand the genetic factors underlying several forms of degenerative brain disease, including Parkinson’s disease and motor neuron disease. He discovered that a mutation in the gene for amyloid precursor protein (APP) caused deposits of a substance called amyloid to form in brain tissue, associated with early-onset Alzheimer’s. Deposits of amyloid, which kills brain cells, later proved to be a primary cause of the disease.

Sir John was elected a Member of the UK Academy of Medical Sciences in 2008, a Fellow of the UK Royal Society in 2009, of the Institute of Biology (now known as the UK Royal Society of Biology) in 2011 and of the European Molecular Biology Organization in 2015. He has received numerous awards including the Dan David Prize (2014), the Thudichum Medal (2015), the Hartwig Piepenbrock-DZNE Prize (2015) and the Helis Prize (2016). In recognition of his groundbreaking research in neurodegeneration, Sir John was awarded the prestigious Breakthrough Prize in Life Sciences in 2016 and the Brain Prize in 2018. In 2022, he received a Knighthood in the New Year’s Honours for his significant contributions to human health and dementia research. Additionally, he was conferred an Honorary Doctorate by HKUST in 2020 and an Honorary Doctorate by the University of Helsinki in 2022, both in acknowledgment of his exceptional research achievements.


Co-organizer

Hong Kong Center for Neurodegenerative Diseases (HKCeND)


For Attendees' Attention

Seating is on a first come, first served basis.

Abstract

Allegory, one might posit, is inherently spatial, insofar as the establishment of an “other” meaning for a given text will involve matters of place and displacement, dislocation, and dispersal, as well as hierarchies of meaning that may be imagined in architectural or topographical terms. In this talk, Robert T. Tally Jr. will discuss the significance of allegory for spatial literary studies, broadly speaking. Drawing on the work of Fredric Jameson, Tally examines the ways that literary texts serve as cognitive maps that not only figuratively chart the social spaces represented, but also offer inherently spatial allegories by which to make sense of their world. The spaces in question are not necessarily geographical, but are often established as relations (e.g., interior-exterior, public-private, high-low, here-there, and so on). Tally will look at Lu Xun’s 1918 short story “Diary of a Madman,” as well as Jameson’s discussion of it, in order to illustrate these connections. In the situation of the diary and its reading, Lu Xun’s tale evokes different aspects of spatial allegory, which in turn suggest multiple pathways for literary cartography and its study.

Biography

Robert T. Tally Jr. is Professor of English at Texas State University. He is the author of many books, including Topophrenia: Place, Narrative, and the Spatial Imagination (2019); Spatiality (2013); Utopia in the Age of Globalization (2013), and the edited collection, the Routledge Handbook of Literature and Space (2017), each of which is now available in Chinese translation. Tally is also the general editor of “Geocriticism and Spatial Literary Studies,” a Palgrave Macmillan book series.

Join us for a fascinating 1-hour guided tour of the Library’s “Lost and Found in Hong Kong: The Unsung Chinese Heroes at D-Day” Exhibition! The exhibition curators will guide you through Lam Ping-yu’s life story and how it weaves into Hong Kong history, illustrating the city's journey towards becoming the metropolis it is today.

The story begins with the discovery of Lam Ping-yu’s diary in a soon-to-be demolished residential building in Hong Kong and unfolds into the recently unearthed history of 24 Chinese naval officers who played a crucial role in the D-Day Landings and Operation Dragoon during the liberation of Southern France. During the tour, you will hear first-hand stories about the realities of war, countless depictions of excitement, frustration, envy, and even romance!

Whether you're a history enthusiast, or simply curious about the contributions of Chinese officers during World War II, this guided tour promises to be a memorable and enlightening experience. Come and explore this fascinating story with us!

The tour will be led by Hugo Petit, Research Assistant at French Centre for Research on Contemporary China (CEFC). The CEFC is hosted by HKUST's School of Humanities and Social Sciences.

As a member of D-Day's editorial team, Hugo worked on the translation and proofreading of materials into French, ahead of D-Day's next exhibition in Normandy, France. He will lead a special tour for French-speaking participants!

Registration: https://lbcube.hkust.edu.hk/ce/event/10936

Please note:

• This is a HMAW 1905-recognized event in the “Personal Enrichment & Community Service” category under the “Self-directed Experience” of HMAW 1905: Behavioral Foundation of University Education: Habits, Mindsets, and Wellness. To receive 1 hour, you must attend the event in full and miss no more than 10 minutes.
• Photos will be taken during the tour. By attending or participating in this event, you are giving your consent to be photographed and you are waiving any and all claims regarding the use of your image by the University.

Enquiry email: library@ust.hk